Vitiligo in children: a review of classification, hypotheses of pathogenesis and treatment Vitiligo em crianças: uma revisão de classificação, hipóteses sobre patogênese e tratamento

An Bras Dermatol. 2005;80(6):633-7. Abstract: Vitiligo is a relatively common dermatologic finding and one that has been observed since ancient times. Depigmentation of the skin, with loss of melanocytes on histology characterizes this disorder. A range of clinical phenotypes lead to varying degrees of morbidity. The cause of vitiligo remains unknown, although an autoimmune pathogenesis seems most likely. Treatment also remains difficult. A number of new therapies show significant potential. In this review, we will focus on the classification of childhood vitiligo, hypotheses of pathogenesis and treatment.